HER2 testing in gastric cancer - results of a German expert meeting

被引：2

作者：

Lordick, F. ^{[1
]}

Al-Batran, S. E. ^{[2
]}

Hofheinz, R. D. ^{[3
]}

Lorenzen, S. ^{[4
]}

Thuss-Patience, P. ^{[5
]}

Baretton, G. B. ^{[6
]}

Dietel, M. ^{[7
]}

Gaiser, T. ^{[8
]}

Kirchner, T. ^{[9
]}

Kreipe, H. H. ^{[10
]}

Quaas, A. ^{[11
]}

Roecken, C. ^{[12
]}

Rueschoff, J. ^{[13
]}

Tannapfel, A. ^{[14
]}

机构：

[1] Univ Klinikum Leipzig, Univ Krebszentrum UCCL, Liebigstr 7, D-04103 Leipzig, Germany

[2] Krankenhaus NW Frankfurt, Frankfurt, Germany

[3] Univ Med Mannheim, Mannheim, Germany

[4] Klinikums Rechts Isar, Med Klin 3, Munich, Germany

[5] Charite, CVK, Charite Ctr Tumormed CC14, Berlin, Germany

[6] Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Inst Pathol, Dresden, Germany

[7] Charite, Inst Pathol, Campus Mitte, Berlin, Germany

[8] Pathol Inst Mannheim, Mannheim, Germany

[9] Univ Munich, Inst Pathol, Munich, Germany

[10] Hannover Med Sch, Inst Pathol, Hannover, Germany

[11] Uniklin Koln, Inst Pathol, Cologne, Germany

[12] Univ Kiel, Inst Pathol, Kiel, Germany

[13] Targos GmbH, Inst Pathol Nordhessen, Kassel, Germany

[14] Ruhr Univ Bochum, Inst Pathol, Georgius Agr Stiftung Ruhr, Berufsgenossenschaftlichen Univ Klinikum, Bochum, Germany

来源：

ZEITSCHRIFT FUR GASTROENTEROLOGIE | 2016年 / 54卷 / 08期

关键词：

gastric cancer; HER2; testing; consensus; quality assurance; trastuzumab; PROGNOSTIC-FACTOR; AMPLIFICATION; ASSOCIATION; CARCINOMA;

D O I：

10.1055/s-0042-110794

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Valid HER2 testing is essential for optimal therapy of patients with HER2 positive gastric cancer and the correct use of first-line treatment. While each breast cancer is routinely being tested for the HER2 status, HER2 testing in gastric cancer has still not become part of the routine and is often only done upon request by the therapist. An interdisciplinary German expert group took the challenges of HER2 testing in gastric cancer as an opportunity to address essential aspects and questions for the practical use of HER2 testing in this indication from the perspective of pathologists and therapists. The recommendations made in this manuscript reflect the consensus of all participants and correspond to their opinions and long-term experience.

引用

页码：791 / 796

页数：6

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