Molecular Characterization of Avian Paramyxovirus Type 1 (Newcastle Disease) Viruses Isolated from Pigeons Between 2000 and 2008 in Slovenia

被引:6
|
作者
Krapez, Uros [1 ]
Steyer, Adela Fratnik [2 ]
Slavec, Brigita [1 ]
Barlic-Maganja, Darja [3 ]
Dovc, Alenka [1 ]
Racnik, Jozko [1 ]
Rojs, Olga Zorman [1 ]
机构
[1] Univ Ljubljana, Inst Poultry Hlth, Fac Vet, SI-1115 Ljubljana, Slovenia
[2] Univ Ljubljana, Virol Unit, Fac Vet, Inst Microbiol & Parasitol, SI-1115 Ljubljana, Slovenia
[3] Univ Primorska, Coll Hlth Care Izola, SI-6310 Izola, Slovenia
关键词
avian paramyxovirus type 1; NDV; F gene sequences; phylogenetic analysis; pigeon; PHYLOGENETIC ANALYSIS; FUSION PROTEIN; GREAT-BRITAIN; COLUMBA-LIVIA; CLEAVAGE SITE; OUTBREAKS; STRAINS; SEQUENCE; CHICKENS; GENOTYPE;
D O I
10.1637/9161-111709-ResNote.1
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Fourteen avian paramyxovirus type 1 (APMV-1; Newcastle disease) viruses isolated from dead free-living and domestic pigeons in Slovenia between 2000 and 2008 were analyzed by a molecular characterization of a part of the fusion protein gene, which included the region encoding the fusion protein cleavage site. Phylogenetic analysis indicated that the Slovene pigeon paramyxovirus type 1 (PPMV-1) viruses do not cluster together but instead are divided into two groups-4bi and 4bii-of sublineage 4b. Nine Slovenian strains were placed in group 4bii. Five other strains clustered together with PPMV-1 from group 4bi. The sequence of the fusion protein cleavage site of all Slovenian strains was typical for pathogenic APMV-1. The (112) RRQKRF(117) motif was present in the strains from group 4bii, whereas strains from group 4bi displayed the (112)GRQKRF(117) motif.
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页码:1075 / 1080
页数:6
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