Direct and label-free detection of solid-phase-bound compounds by using surface-enhanced raman scattering microspectroscopy

被引:40
|
作者
Schmuck, Carsten [1 ]
Wich, Peter
Kuestner, Bernd
Kiefer, Wolfgang
Schluecker, Sebastian
机构
[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany
[2] Univ Wurzburg, Inst Phys Chem, D-97074 Wurzburg, Germany
关键词
analytical methods; Raman spectroscopy; SERS (surface-enhanced Raman scattering); supramolecular chemistry;
D O I
10.1002/anie.200605190
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Graph Presented) Sensitive and specific: By using surface-enhanced Raman scattering (SERS) microspectroscopy, solid-phase-bound compounds can be detected directly and marker-free in a few seconds on a single polystyrene bead. No significant contributions of the matrix are observed, as demonstrated by reference Raman spectra. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:4786 / 4789
页数:4
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