OppA Escherichia coli mutants have osmodependent resistance to aminoglycoside antibiotics

被引：0
|
作者：
Tsuhako, HH
Ferreira, LCS
da Costa, SOP
机构：
[1] Univ Sao Paulo, Dept Microbiol, ICB 2, BR-05508900 Sao Paulo, Brazil
[2] Univ Fed Rio de Janeiro, CCS, Inst Biofis Carlos Chagas Filho, BR-21949900 Rio De Janeiro, Brazil
来源：
GENETICS AND MOLECULAR BIOLOGY | 1998年 / 21卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The oligopeptide permease (OppA) protein was found to be missing in the periplasmic fractions of Escherichia coli kanamycin-resistant mutants selected under high osmotic conditions. The growth behavior of one mutant in media containing kanamycin or the toxic peptide triornithine suggests that OppA and another cell envelope component contribute to the osmolarity-dependent aminoglycoside resistance of E. coli.
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页码：15 / 19
页数：5
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