Organs at risk in lung SBRT

被引:25
|
作者
De Rose, F. [1 ]
Franceschini, D. [1 ]
Reggiori, G. [1 ]
Stravato, A. [1 ]
Navarria, P. [1 ]
Ascolese, A. M. [1 ]
Tomatis, S. [1 ]
Mancosu, P. [1 ]
Scorsetti, M. [1 ,2 ]
机构
[1] Humanitas Canc Ctr & Res Hosp, Radiotherapy & Radiosurg Dept, Milan, Italy
[2] Humanitas Univ, Dept Biomed Sci, Milan, Italy
关键词
Lung SBRT; Dose constraints; Organs at risk; STEREOTACTIC BODY RADIATION; INDUCED BRACHIAL PLEXOPATHY; LOCATED EARLY-STAGE; CHEST-WALL PAIN; DOSE CONSTRAINTS; ABLATIVE RADIOTHERAPY; SPINAL-CORD; PHASE-II; THERAPY; VOLUME;
D O I
10.1016/j.ejmp.2017.04.010
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Lung stereotactic body radiotherapy (SBRT) is an accurate and precise technique to treat lung tumors with high 'ablative' doses. Given the encouraging data in terms of local control and toxicity profile, SBRT has currently become a treatment option for both early stage lung cancer and lung oligometastatic disease in patients who are medically inoperable or refuse surgical resection. Dose-adapted fractionation schedules and ongoing prospective trials should provide further evidence of SBRT safety trying to reduce toxicities and complications. In this heterogeneous scenario, a non-systematic review of dose constraints for lung SBRT was performed, including the main organs at risk in the thorax. (C) 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:131 / 138
页数:8
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