Highly stereoselective 7-membered ring synthesis based upon the oxidopyrylium-alkene [5+2]cycloaddition reaction

被引：0
|
作者：
Ohmori, N [1 ]
Miyazaki, T [1 ]
Kojima, S [1 ]
Ohkata, K [1 ]
机构：
[1] Hiroshima Univ, Grad Sch Sci, Dept Chem, Higashihiroshima 7398526, Japan
来源：
CHEMISTRY LETTERS | 2001年 / 09期
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D O I：
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The [5+2]cycloaddition reaction of 2-substituted-3-oxidopyrylium betaine with dialkyl fumarates was found to proceed with stereoselectivity up to 15.5:1. The stereoselectivity became higher as either the 2-substituent of the 3-oxidopyrylium or the alkoxy group of the fumarate became larger. The stereoselectivity could be rationalized by considering these steric effects.
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页码：906 / 907
页数：2
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