Presence of a high amount of stroma within BRAF-mutated colon cancer predicts for very poor survival

被引:0
|
作者
van Pelt, G. [1 ]
Huijbers, A. [1 ]
Domingo, E. [1 ]
Kerr, R. [1 ]
Johnstone, E. [1 ]
Tomlinson, I. [1 ]
Kerr, D. [1 ]
Tollenaar, R. [1 ]
Mesker, W. [1 ]
机构
[1] LUMC, Surg, Leiden, Netherlands
关键词
D O I
暂无
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
PS-20-017
引用
收藏
页码:S163 / S163
页数:1
相关论文
共 50 条
  • [1] A BRAF-mutated gene expression signature identifies BRAF wild type colon cancer patients with poor prognosis
    Popovici, Vlad
    Budinska, Eva
    Tejpar, Sabine
    Roth, Arnaud
    Bosman, Fredrik
    Weinrich, Scott
    Hodgson, Graeme
    Delorenzi, Mauro
    CANCER RESEARCH, 2011, 71
  • [2] Progression-free survival in metastatic, BRAF-mutated colorectal cancer
    Morris, Van Karlyle
    Overman, Michael J.
    Maru, Dipen M.
    Kopetz, Scott
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (04)
  • [3] Leptomeningeal carcinomatosis as a rare metastatic spreading of BRAF-mutated microsatellite stable colon cancer
    Hoeblinger, Aksana
    Weber, Stephanie
    Tschirner, Florian
    Kroeber, Stefan
    Streetz, Konrad
    ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2017, 55 (07): : 667 - 674
  • [4] BRAF-mutated, Microsatellite-stable Adenocarcinoma of the Proximal Colon: An Aggressive Adenocarcinoma With Poor Survival, Mucinous Differentiation, and Adverse Morphologic Features
    Pai, Reetesh K.
    Jayachandran, Priya
    Koong, Albert C.
    Chang, Daniel T.
    Kwok, Shirley
    Ma, Lisa
    Arber, Daniel A.
    Balise, Raymond R.
    Tubbs, Raymond R.
    Shadrach, Bonnie
    Pai, Rish K.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2012, 36 (05) : 744 - 752
  • [5] Progression-Free Survival Remains Poor Over Sequential Lines of Systemic Therapy in Patients With BRAF-Mutated Colorectal Cancer
    Morris, Van
    Overman, Michael J.
    Jiang, Zhi-Qin
    Garrett, Christopher
    Agarwal, Shweta
    Eng, Cathy
    Kee, Bryan
    Fogelman, David
    Dasari, Arvind
    Wolff, Robert
    Maru, Dipen
    Kopetz, Scott
    CLINICAL COLORECTAL CANCER, 2014, 13 (03) : 164 - 171
  • [6] Allied therapies against BRAF-mutated advanced colon cancer: the right plans to win the battle
    Kourie, Hampig Raphael
    Gharios, Joseph
    Kattan, Joseph
    COLORECTAL CANCER, 2016, 5 (02) : 53 - 55
  • [7] Application of trastuzumab emtansine in HER-2-positive and KRAS/BRAF-mutated colon cancer cells
    Chung, Yuan-Chiang
    Chiu, Hsi-Hsiung
    Wei, Wan-Chen
    Chang, King-Jen
    Chao, Wei-Ting
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2020, 50 (08)
  • [8] High Wnt2 Expression Confers Poor Prognosis in Colorectal Cancer, and Represents a Novel Therapeutic Target in BRAF-Mutated Colorectal Cancer
    Liu, Huan
    Zhang, Lihua
    Wang, Ye
    Wu, Rendi
    Shen, Chenjie
    Li, Guifang
    Shi, Shiqi
    Mao, Yong
    Hua, Dong
    MEDICINA-LITHUANIA, 2023, 59 (06):
  • [9] Original Research Tumour mutational burden predicts resistance to EGFR/ BRAF blockade in BRAF-mutated microsatellite stable metastatic colorectal cancer
    Randon, Giovanni
    Intini, Rossana
    Cremolini, Chiara
    Elez, Elena
    Overman, Michael J.
    Lee, Jeeyun
    Manca, Paolo
    Bergamo, Francesca
    Pagani, Filippo
    Antista, Maria
    Angerilli, Valentina
    Ros Montana, Francisco Javier
    Lavacchi, Daniele
    Boccaccino, Alessandra
    Fuca, Giovanni
    Brich, Silvia
    Cattaneo, Laura
    Fassan, Matteo
    Pietrantonio, Filippo
    Lonardi, Sara
    EUROPEAN JOURNAL OF CANCER, 2022, 161 : 90 - 98
  • [10] Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients
    Mesker, Wilma E.
    Liefers, Gerrit-Jan
    Junggeburt, Jan M. C.
    van Pelt, Gabi W.
    Alberici, Paola
    Kuppen, Peter J. K.
    Miranda, Noel F.
    van Leeuwen, Karin A. M.
    Morreau, Hans
    Szuhai, Karoly
    Tollenaar, Rob A. E. M.
    Tanke, Hans J.
    CELLULAR ONCOLOGY, 2009, 31 (03) : 169 - 178