Immunoglobulin A Nephropathy Associated with Plasmodium falciparum Malaria

被引：8

作者：

Yoo, Dong Eun ^{[1
]}

Kim, Jeong Ho ^{[2
]}

Kie, Jeong Hae ^{[3
]}

Park, Yoonseon ^{[2
]}

Chang, Tae Ik ^{[2
]}

Oh, Hyung Jung ^{[1
]}

Kim, Seung Jun ^{[1
]}

Yoo, Tae-Hyun ^{[1
]}

Choi, Kyu Hun ^{[1
]}

Kang, Shin-Wook ^{[1
]}

Han, Seung Hyeok ^{[1
]}

机构：

[1] Yonsei Univ, Coll Med, Dept Internal Med, Seoul 120752, South Korea

[2] Natl Hlth Insurance Corp Ilsan Hosp, Dept Internal Med, Goyang, South Korea

[3] Natl Hlth Insurance Corp Ilsan Hosp, Dept Pathol, Goyang, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2012年 / 27卷 / 04期

关键词：

Glomerulonephritis; IgA nephropathy; Malaria; Plasmodium falciparum; ALPHA-GALACTOSYL ANTIBODIES; IGA-NEPHROPATHY; IMMUNE-COMPLEXES; INFECTION; GLOMERULONEPHRITIS; PATHOGENESIS;

D O I：

10.3346/jkms.2012.27.4.446

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laboratory tests after recovery from malaria showed disappearance of urinary abnormalities and normalization of kidney function. Our findings suggest that malaria infection might be associated with IgA nephropathy.

引用

页码：446 / 449

页数：4

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