Cutaneous leishmaniasis in Nepal:: Leishmania major as a cause

被引：15

作者：

Kumar, Rajesh ^{[1
]}

Ansari, Nasim Akhtar ^{[1
]}

Avninder, Singh ^{[1
]}

Ramesh, V. ^{[2
,3
,4
]}

Salotra, Poonam ^{[1
]}

机构：

[1] Inst Pathol ICMR, New Delhi 110029, India

[2] Safdarjang Hosp, Dept Dermatol, New Delhi 110029, India

[3] Safdarjang Hosp, Reg STD Ctr, New Delhi 110029, India

[4] VM Med Coll, New Delhi 110029, India

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2008年 / 102卷 / 02期

关键词：

cutaneous leishmaniasis; Leishmania; diagnosis; PCR; RFLP; Nepal;

D O I：

10.1016/j.trstmh.2007.10.017

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Nepal is endemic for visceral. leishmaniasis; however, recently a solitary report of cutaneous leishmaniasis (CL) was recorded. The present report describes a CL case in a Nepalese woman, initially referred as a case of basal cell carcinoma. Histopathological examination, culture and PCR analysis of lesions revealed it to be a case of CL. Molecular methods, including kDNA PCR, ITS-1 PCR-RFLP and sequence analysis, revealed the species as Leishmania major. The patient was cured with sodium stibogluconate. This report suggests that the extent to which L. major causes CL in the Indian subcontinent needs to be monitored. (c) 2007 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

引用

页码：202 / 203

页数：2

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