An endoplasmic reticulum-targeting fluorescent probe for imaging •OH in living cells

被引：24
|
作者：
Zhao, Yanyan [1 ,2 ]
Li, Hongyu [1 ]
Chai, Ziyin [1 ]
Shi, Wen [1 ,2 ]
Li, Xiaohua [1 ]
Ma, Huimin [1 ,2 ]
机构：
[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 47期
关键词：
UNFOLDED PROTEIN RESPONSE; HYDROGEN-PEROXIDE; STRESS; MITOCHONDRIA; AUTOPHAGY;
D O I：
10.1039/d0cc00233j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The hydroxyl radical ((OH)-O-center dot) in the endoplasmic reticulum has not been studied thoroughly due to the lack of proper methods. Here, an endoplasmic reticulum-targeting fluorescent probe for detecting (OH)-O-center dot is reported. With this probe, the action of (OH)-O-center dot in the endoplasmic reticulum has been imaged in living cells.
引用
收藏
页码：6344 / 6347
页数：4
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