Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children

被引：9

作者：

Kuntz, Martin ^{[1
]}

Kohlfuerst, Daniela S. ^{[2
]}

Feiterna-Sperling, Cornelia ^{[3
]}

Krueger, Renate ^{[3
]}

Baumann, Ulrich ^{[4
]}

Buchtala, Laura ^{[5
]}

Elling, Roland ^{[1
]}

Grote, Veit ^{[6
]}

Huebner, Johannes ^{[6
]}

Hufnagel, Markus ^{[1
]}

Kaiser-Labusch, Petra ^{[5
]}

Liese, Johannes ^{[7
]}

Otto, Eva-Maria ^{[8
]}

Rose, Markus A. ^{[9
,14
]}

Schneider, Christian ^{[1
]}

Schuster, Volker ^{[10
]}

Seidl, Maximilian ^{[1
]}

Sommerburg, Olaf ^{[11
]}

Vogel, Markus ^{[12
,15
]}

von Bernuth, Horst ^{[3
]}

Wei, Michael ^{[8
]}

Zimmermann, Theodor ^{[13
]}

Nieters, Alexandra ^{[1
]}

Zenz, Werner ^{[2
]}

Henneke, Philipp ^{[1
]}

机构：

[1] Univ Freiburg, Freiburg, Germany

[2] Med Univ Graz, Graz, Austria

[3] Charite Univ Med Berlin, Berlin, Germany

[4] Hannover Med Sch, Hannover, Germany

[5] Hess Kinderklin, Bremen, Germany

[6] Dr von Hauner Childrens Hosp, Munich, Germany

[7] Univ Childrens Hosp, Wurzburg, Germany

[8] Childrens Hosp, Cologne, Germany

[9] Goethe Univ Frankfurt, Frankfurt, Germany

[10] Univ Leipzig, Leipzig, Germany

[11] Heidelberg Univ, Heidelberg, Germany

[12] Heinrich Heine Univ, Dusseldorf, Germany

[13] Friedrich Alexander Univ Erlangen Nurnberg, Erlangen, Germany

[14] Olga Childrens Hosp, Stuttgart, Germany

[15] Hosp Neuwerk, Monchengladbach, Germany

来源：

EMERGING INFECTIOUS DISEASES | 2020年 / 26卷 / 03期

关键词：

CERVICOFACIAL LYMPHADENITIS; OPPORTUNISTIC PATHOGENS; ANTIBIOTIC-TREATMENT; DISEASE; SUSCEPTIBILITY; INFECTION; SURVEILLANCE; DIAGNOSIS; WATER;

D O I：

10.3201/eid2603.191388

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nontuberculous mycobacteria (NTM) are an emerging cause of infections, including chronic lymphadenitis in children. To identify risk factors for NTM lymphadenitis, particularly complicated disease, we collected epidemiologic, clinical, and microbiological data on 138 cases of NTM lymphadenitis in children across 13 centers in Germany and Austria. We assessed lifestyle factors but did not identify specific risk behaviors. We noted that more cases of NTM lymphadenitis occurred during cold months than during warm months. Moreover, we noted female sex and age <5.5 years as potential risk factors. Complete extirpation of the affected lymph node appeared to be the best therapeutic measure. We integrated the study data to develop a simple risk score to predict unfavorable clinical outcomes for NTM lymphadenitis.

引用

页码：579 / 586

页数：8

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