Risk factors of stroke mortality: A 40-year follow-up of the Corfu cohort from the Seven-Countries Study

被引：12
|
作者：
Panagiotakos, DB
Chrysohoou, C
Pitsavos, C
Menotti, A
Dontas, A
Skoumas, J
Stefanadis, C
Toutouzas, P
机构：
[1] Univ Athens, Sch Med, Dept Cardiol, GR-11527 Athens, Greece
[2] Ctr Studies Age Related Changes Man, GR-11527 Athens, Greece
[3] Assoc Cardiac Res, Rome, Italy
来源：
NEUROEPIDEMIOLOGY | 2003年 / 22卷 / 06期
关键词：
cholesterol; mortality; physical activity; pulse pressure; Seven-Countries Study; stroke;
D O I：
10.1159/000072922
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The present work evaluates several risk factors for stroke mortality based on a 40-year follow-up of the Corfu cohort from the Seven-Countries Study. The population studied in this analysis consisted of 529 rural men (49.7 +/- 5.7 years old) enrolled at 1961. The death rate at the end of follow-up was 87.1% (i.e. 461 deaths out of 529 participants). Of 529 cardiovascular-disease-free men at entry, 74 (14%) died because of hemorrhagic or thrombotic stroke. Age (HR = 1.11/year, p < 0.001), pulse pressure (HR = 1.16/5 mm Hg, p < 0.001), total serum cholesterol levels (HR = 0.81/10 mg/dl, p < 0.01) and presence of physical activity (HR = 0.59, p < 0.05), showed a statistically significant association with fatal stroke events. In conclusion, age, pulse pressure levels, physical activity (protective) and total serum cholesterol levels (protective) were significantly related with 40-year stroke mortality. Copyright (C) 2003 S. Karger AG, Basel.
引用
收藏
页码：332 / 338
页数：7
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