Wound healing activity of gel extract female coconut flower in mice (Mus musculus)

The purpose of this study to analyzes the wound healing activity of female coconut flower (Cocos nucifera L.) gel extract in male mice (Mus musculus). Treatment by applying the gel to wound with a concentration of 0% (negative control), 25%, 50%, 75%, 100%, and povidone-iodine 10% as a positive control. The measurement of the wound includes the length, width, and area every 24 hours until the wound is completely absent and the third data calculated become healing percentage and wound healing speed, analyzed by statistic (One Way ANOVA). The results show that the percentage and wound healing speed in male mice were not significantly different between all treatments with the positive control (povidone-iodine 10%). It can be concluded that female coconut flower extract (Cocos nucifera L.) is effective against wound healing in male mice (Mus musculus) because it has the same ability as povidone-iodine to wound healing. The female coconut flower extract has a high flavonoid content as antioxidant which can inhibit inflammation in the wound. This research can provide great benefits for people around the world that can be developed into effective, inexpensive wound healing products with abundant and easily available ingredients in the surrounding environment and can compete in the world.