Porous Hematite Nanostructures as Drug Carriers for Biodegradable Implants

被引：0
|
作者：
Lozhkomoev, A. S. [1 ]
Kazantsev, S. O. [1 ]
Bakina, O., V [1 ]
Rubtsov, K., V [1 ]
机构：
[1] Inst Strength Phys & Mat Sci SB RAS, Tomsk 634055, Russia
来源：
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON PHYSICAL MESOMECHANICS. MATERIALS WITH MULTILEVEL HIERARCHICAL STRUCTURE AND INTELLIGENT MANUFACTURING TECHNOLOGY | 2020年 / 2310卷
关键词：
D O I：
10.1063/5.0034417
中图分类号：
TH [机械、仪表工业];
学科分类号：
0802 ;
摘要：
'The present study deals with porous hematite nanostructures as antimicrobial drug delivery systems. Obtained nanoparticles have been analyzed by Transmission Electron Microscopy (TEM) and X-Ray Diffraction analysis. Porous ellipsoidal particles with a size range of 50-200 nm, which consist of 2-10 nm fragments, were observed. Drug adsorption onto the hematite nanostructures surface has been examined using penicillin and vancomycin as a model systems. Obtained adsorption isotherms represent weak interaction between adsorbate and adsorbent. The maximum adsorption capacities of penicillin and vancomycin were 8 and 6 mg/g respectively. The results suggest that synthesized hematite nanostructures could be used as drug carriers into Fe-Fe2O3 implants.
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页数：4
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