Approach to the Management of Patients With Hidradenitis Suppurativa: A Consensus Document

被引:30
|
作者
Alavi, Afsaneh [1 ]
Lynde, Charles [1 ]
Alhusayen, Raed [1 ]
Bourcier, Marc [2 ]
Delorme, Isabelle [3 ]
George, Ralph [4 ]
Gooderham, Melinda [5 ]
Gulliver, Wayne [6 ]
Kalia, Sunil [7 ]
Marcoux, Danielle [8 ,9 ]
Poulin, Yves [10 ]
机构
[1] Univ Toronto, Dept Med Dermatol, Toronto, ON, Canada
[2] Sherbrooke Univ, Sherbrooke, PQ, Canada
[3] Clin Dre Isabelle Delorme, Drummondville, PQ, Canada
[4] St Michaels Hosp, Div Gen Surg, Toronto, ON, Canada
[5] Queens Univ, Dept Med, Kingston, ON, Canada
[6] Mem Univ Newfoundland, Dept Med, St John, NF, Canada
[7] Univ British Columbia, Div Dermatol & Skin Sci, Dept Med, Vancouver, BC, Canada
[8] Univ Montreal, Div Dermatol, Dept Pediat, Montreal, PQ, Canada
[9] CHU Ste Justine, Montreal, PQ, Canada
[10] Ctr Rech Dermatol Quebec Metropolitain, Quebec City, PQ, Canada
关键词
hidradenitis suppurativa; inflammatory nodules; abscesses; antibacterials; anti-tumour necrosis factor therapies; biologics; multidisciplinary approach; CONTROLLED CROSSOVER TRIAL; ACNE INVERSA; DOUBLE-BLIND; CLINDAMYCIN; THERAPY; MODERATE; ADALIMUMAB; RIFAMPICIN; QUALITY; OPTIONS;
D O I
10.1177/1203475417716117
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Hidradenitis suppurativa (HS) is a painful, debilitating, and poorly understood condition, which is suboptimally diagnosed, managed, and treated. Evidence supporting various treatment modalities is sparse. Objectives: To incorporate scientific evidence and expert opinions to develop useful guidance for the evaluation and management of patients with HS. Methods: An expert panel of Canadian dermatologists and surgeons developed statements and recommendations based on available evidence and clinical experience. The statements and recommendations were subjected to analysis and refinement by the panel, and voting was conducted using a modified Delphi technique with a prespecified cutoff agreement of 75%. Results: Ten specific statements and recommendations were accepted by the expert panel. These were grouped into 4 domains: diagnosis and assessment, treatment and management, comorbidities and a multidisciplinary approach, and education. Conclusions: These statements and recommendations will serve to increase awareness of HS and provide a framework for decisions involving diagnosis and management. Evidence suggests that antibacterial and anti-tumour necrosis factor therapies are effective in the treatment of HS. This is supported by the clinical experience of the authors. Further clinical research and the establishment of multidisciplinary management teams will continue to advance management of HS in Canada.
引用
收藏
页码:513 / 524
页数:12
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