New approach to the progesterone BCD-ring system by utilizing a tandem transannular radical cyclization

被引：10
|
作者：
Tomida, S [1 ]
Doi, T [1 ]
Takahashi, T [1 ]
机构：
[1] Tokyo Inst Technol, Dept Chem Engn, Meguro Ku, Tokyo 1528552, Japan
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 12期
基金：
日本学术振兴会;
关键词：
radicals and radical reactions; transannular reactions; molecular modelling mechanics; steroids and sterols;
D O I：
10.1016/S0040-4039(99)00187-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of rile progesterone BCD-ring system utilizing a tandem transannular radical cyclization and its diastereoselectivity based on MM2 transition state model calculations (flexible model) are described. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2363 / 2366
页数：4
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