Low Cost Screening for Features of Prodromal Parkinson's Disease in General Medical Practice in Italy

被引：5

作者：

Baldin, Elisa ^{[1
]}

Zenesini, Corrado ^{[1
]}

Bauleo, Salvatore ^{[2
]}

Montanari, Federico ^{[2
]}

Santi, Sandra ^{[2
]}

Spampinato, Maurizio ^{[2
]}

Cortelli, Pietro ^{[3
,4
]}

D'Alessandro, Roberto ^{[1
]}

Ascherio, Alberto ^{[5
,6
,7
,8
]}

机构：

[1] IRCCS Ist Sci Neurol Bologna, Epidemiol & Stat Unit, Via Altura 3, I-40139 Bologna, Italy

[2] ASL Bologna, Primary Care Dept, Casalecchio Reno Dist, Bologna, Italy

[3] Bellaria Hosp Univ Bologna, Unit Neurol, Dept Biomed & Neuromotor Sci, Bologna, Italy

[4] IRCCS Ist Sci Neurol Bologna, Unit Neurol, Bologna, Italy

[5] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA

[6] Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

[7] Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA

[8] Harvard Med Sch, Boston, MA 02115 USA

来源：

JOURNAL OF PARKINSONS DISEASE | 2020年 / 10卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Parkinson's disease; epidemiology; health policy and practice; SUBJECTIVE COGNITIVE CONCERNS; MDS RESEARCH CRITERIA; MEMORY;

D O I：

10.3233/JPD-191868

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The aim of the study was to determine the feasibility of screening older adults attending general medical practice for features suggesting prodromal Parkinson's disease (PD). Four general practitioners recruited 392 subjects aged =60 years, attending their primary clinics. A self-administered questionnaire collected information on history of probable rapid eye movements sleep behavior disorder (pRBD), constipation, risk markers for PD, and on subjective cognitive function. Olfactory function was tested. Constipation (27.8%), and hyposmia (19.9%), but not pRBD (4.3%), were more prevalent with age. Further supporting the feasibility of a longitudinal study, 299 subjects agreed to be followed.

引用

页码：711 / 715

页数：5

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