Temoporfin (Foscan®, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin)-A Second-generation Photosensitizer

被引：260
|
作者：
Senge, Mathias O. [1 ,2 ]
Brandt, Johan C. [2 ]
机构：
[1] St James Hosp, Trinity Ctr Hlth Sci, Inst Mol Med, Trinity Coll Dublin, Dublin 8, Ireland
[2] Trinity Coll Dublin, Sch Chem, SFI Tetrapyrrole Lab, Dublin 2, Ireland
来源：
PHOTOCHEMISTRY AND PHOTOBIOLOGY | 2011年 / 87卷 / 06期
基金：
爱尔兰科学基金会;
关键词：
MEDIATED PHOTODYNAMIC THERAPY; SQUAMOUS-CELL CARCINOMA; TETRA-HYDROXYPHENYL-CHLORIN; MALIGNANT PLEURAL MESOTHELIOMA; M-TETRAHYDROXYPHENYL CHLORIN; LASER-INDUCED FLUORESCENCE; HUMAN TUMOR XENOGRAFTS; HIGH-GRADE DYSPLASIA; RESONANCE MASS-SPECTROMETRY; OPTIMIZING LIGHT DOSIMETRY;
D O I：
10.1111/j.1751-1097.2011.00986.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review traces the development and study of the second-generation photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin through to its acceptance and clinical use in modern photodynamic (cancer) therapy. The literature has been covered up to early 2011.
引用
收藏
页码：1240 / 1296
页数：57
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