Serum Cryptococcal Antigen Confirmed Pulmonary Cryptococcosis in an Immune-competent Adult Firstly Misdiagnosed of Tuberculosis from a Lung Biopsy: a Case Report and Literature Review

被引：0

作者：

Ge, Yan L. ^{[1
]}

Liu, Cong H. ^{[2
]}

Wang, Meng H. ^{[3
]}

Li, Zhen Z. ^{[1
]}

Li, Hong L. ^{[1
]}

Cui, Zi Y. ^{[1
]}

Zhang, Hai F. ^{[1
]}

Zhu, Xiao Y. ^{[1
]}

Zhang, Xue ^{[1
]}

Yu, Hua L. ^{[1
]}

Fu, Ai S. ^{[1
]}

Wang, Hong Y. ^{[1
]}

机构：

[1] North China Univ Sci & Technol Affiliated Hosp, Dept Resp Med, Jianshe Rd 73, Tangshan 063000, Hebei, Peoples R China

[2] North China Univ Sci & Technol Affiliated Hosp, Dept Internal Med, Tangshan, Hebei, Peoples R China

[3] North China Univ Sci & Technol Affiliated Hosp, Dept Hosp Informat Management, Tangshan, Hebei, Peoples R China

来源：

CLINICAL LABORATORY | 2018年 / 64卷 / 11-12期

关键词：

cryptococcal pneumonia; cryptococcus neoformans; cryptococcal antigen; IMMUNOCOMPETENT PATIENT; CT FINDINGS;

D O I：

10.7754/Clin.Lab.2018.180616

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: Cryptococcal pneumonia is an uncommon lesion in immune-competent adults. Histological evidence of Cryptococcus neoformans is a gold criterion for diagnosis. Here we report a case firstly misdiagnosed as tuberculosis from a lung biopsy. Methods: Chest computed tomography (CT) scan and CT-guided puncture were performed for diagnosis and blood tests explored for the latent etiology. Results: Chest CT scan images showed multiple nodules in the left peripheral lower lobe. Histopathology demonstrated multiple granulomatous inflammatory response lacking evidence of Cryptococcus neoformans, acid-fast staining was negative, serum cryptococcal antigen was positive. Conclusions: Serum cryptococcal antigen has high specificity in cryptococcal pneumonia.

引用

页码：1947 / 1949

页数：3

共 9 条

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