The effects of psychoeducational interventions on caregivers of children with cancer: A meta-analysis of randomized controlled trials

This meta-analysis aims to evaluate the best available evidence concerning the effects of psychoeducational interventions (PEIs) on the psychosocial and coping outcomes for caregivers of pediatric oncology patients. A literature search was performed using 11 databases, from inception to June 2017. Keywords such as pediatric, caregiver, parents, cancer, and intervention were used. Only randomized controlled trials (RCTs) were included. Studies with full text available online in English and those conducted of caregivers of children diagnosed with any form of cancer were included. Eleven RCTs were included in the analysis. Our meta-analysis revealed that PEIs have small to large effects on three outcomes, including post-traumatic stress symptoms (PTSSs), mood, and problem-solving skills. However, the outcomes from PEI were not superior to the usual standard of care for anxiety, depression, and social support. Our meta-analysis provided moderate evidence that PEI enhances psychological and coping outcomes. Because coping affects both physical and psychological health, health care professionals could consider including coping as a core component in PEI delivered to caregivers of children with cancer.