One-pot, three-component condensation reaction in water: An efficient and improved procedure for the synthesis of pyran annulated heterocyclic systems

被引:49
|
作者
Shaabani, Ahmad [1 ]
Samadi, Sima [1 ]
Rahmati, Abbas [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Dept Chem, Tehran, Iran
关键词
1,3-dimethylbarbituric acid; 4-hydroxycoumarin; 4-hydroxy-6-methylpyrone; pyran annulated heterocyclic system; three-component reaction; water;
D O I
10.1080/00397910601039242
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Environmentally friendly three-component condensation reactions of an activated C-H acid, an aldehyde, and alkyl nitriles to afford the corresponding pyran annulated heterocyclic systems in water in good yields, avoiding the addition of any catalyst, are reported.
引用
收藏
页码:491 / 499
页数:9
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