Nutrition Support of Children With Chronic Liver Diseases: A Joint Position Paper of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition

被引:62
|
作者
Mouzaki, Marialena [1 ]
Bronsky, Jiri [2 ,3 ]
Gupte, Girish [4 ]
Hojsak, Iva [5 ]
Jahnel, Jorg [6 ]
Pai, Nikhil [7 ]
Quiros-Tejeira, Ruben E. [8 ]
Wieman, Renee [1 ]
Sundaram, Shikha [9 ]
机构
[1] Univ Cincinnati, Sch Med, Cincinnati Childrens Hosp Med Ctr, 3333 Burnet Ave, Cincinnati, OH 45229 USA
[2] Charles Univ Prague, Dept Pediat, Fac Med 2, Prague, Czech Republic
[3] Motol Univ Hosp, Prague, Czech Republic
[4] Birmingham Childrens Hosp, Liver Unit, Birmingham, W Midlands, England
[5] Univ Zagreb, Childrens Hosp Zagreb, Sch Med, Zagreb, Croatia
[6] Med Univ Graz, Dept Pediat & Adolescent Med, Graz, Austria
[7] McMaster Univ, Dept Pediat, Hamilton, ON, Canada
[8] Univ Nebraska Med Ctr, Childrens Hosp & Med Ctr, Omaha, NE USA
[9] Univ Colorado, Childrens Hosp Colorado, Sch Med, Aurora, CO USA
关键词
cirrhosis; frailty; malnutrition; metabolic bone disease; nutrient deficiencies; VITAMIN-E-DEFICIENCY; BONE-MINERAL DENSITY; POLYETHYLENE GLYCOL-1000 SUCCINATE; RESTING ENERGY-EXPENDITURE; BODY-COMPOSITION; GRIP STRENGTH; HEPATIC-ENCEPHALOPATHY; PREPUBERTAL CHILDREN; K DEFICIENCY; FATTY-ACIDS;
D O I
10.1097/MPG.0000000000002443
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Chronic liver disease places patients at increased risk of malnutrition that can be challenging to identify clinically and treat. Nutrition support is a key aspect of the management of these patients as it has an impact on their quality of life, morbidity, and mortality. There are significant gaps in the literature regarding the optimal nutrition support for patients with different types of liver diseases and the impact of these interventions on long-term outcomes. This Position Paper summarizes the available literature on the nutritional aspects of the care of patients with chronic liver diseases. Specifically, the challenges associated with the nutritional assessment of these subjects are discussed, and recently investigated approaches to determining the patients' nutritional status are reviewed. Furthermore, the pathophysiology of the malnutrition seen in the context of chronic liver disease is summarized and monitoring, as well as treatment, recommendations are provided. Lastly, suggestions for future research studies are described.
引用
收藏
页码:498 / 511
页数:14
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