A Bayesian analysis of multivariate doubly-interval-censored dental data

被引：24
|
作者：
Komárek, A
Lesaffre, E
Härkänen, T
Declerck, D
Virtanen, JI
机构：
[1] Catholic Univ Louvain, Ctr Biostat, B-3000 Louvain, Belgium
[2] Natl Publ Hlth Inst, FIN-00300 Helsinki, Finland
[3] Katholieke Univ Leuven, Sch Dent, B-3000 Louvain, Belgium
[4] Univ Helsinki, Inst Dent, FIN-00014 Helsinki, Finland
来源：
BIOSTATISTICS | 2005年 / 6卷 / 01期
关键词：
Bayesian analysis; intensity models; multivariate doubly-interval-censored data;
D O I：
10.1093/biostatistics/kxh023
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A Bayesian survival analysis is presented to examine the effect of fluoride-intake on the Lime to caries development of the permanent first molars in children between 7 and 12 years of age using a longitudinal study conducted in Flanders. Three problems needed to be addressed. Firstly, since the emergence. time of a tooth and the time it experiences caries were recorded yearly, the time to canes is doubly interval censored. Secondly, due to the setup of the study, many emergence times were left-censored. Thirdly, events on teeth of the same child are dependent. Our Bayesian analysis is a modified version of the intensity model of Harkanen et al. (2000, Scandinavian Journal of Statistics 27, 577-588). To tackle the problem of the large number of left-censored observations a similar Finnish data set was introduced. Our analysis shows no convincing effect of fluoride-intake on caries development.
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页码：145 / 155
页数：11
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