BIOPEP-UWM Virtual-A Novel Database of Food-Derived Peptides with In Silico-Predicted Biological Activity

被引:20
|
作者
Minkiewicz, Piotr [1 ]
Iwaniak, Anna [1 ]
Darewicz, Malgorzata [1 ]
机构
[1] Univ Warmia & Mazury, Dept Food Biochem, Plac Cieszynski 1, PL-10726 Kortowo, Olsztyn, Poland
来源
APPLIED SCIENCES-BASEL | 2022年 / 12卷 / 14期
关键词
peptides; bioactivity; taste; molecular docking; in silico predictions; database; PROTEINS;
D O I
10.3390/app12147204
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The novel BIOPEP-UWM Virtual database is designed as a repository of peptide sequences whose bioactivity or taste information was the result of in silico predictions. It is a tool complementary to the existing BIOPEP-UWM database summarizing the results of experimental data on bioactive peptides. The layout and organization of the new database are identical to those of the existing BIOPEP-UWM database of bioactive peptides. The peptide data record includes the following information: name; sequence and function information (understood as information about the predicted target biomacromolecule); bibliographic data with the reference paper describing the peptide; additional information, including the peptide structure, annotated using chemical codes as well as the specification of the method used for bioactivity prediction; information about other activities discovered experimentally or predicted using computational methods; peptide taste (if available); and a database reference tab providing information about compound annotations in other databases (if available).
引用
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页数:9
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