Orientation adaptation of eye movement-related vestibular neurons due to prolonged head tilt

被引:5
|
作者
Kolesnikova, Olga V. [1 ]
Raphan, Theodore [2 ]
Cohen, Bernard [1 ]
Yakushin, Sergei B. [1 ]
机构
[1] Mt Sinai Sch Med, Dept Neurol, New York, NY 10029 USA
[2] CUNY Brooklyn Coll, Dept Comp & Informat Sci, New York, NY USA
关键词
adaptation; monkey; VOR; gravity; ANGULAR VESTIBULOOCULAR REFLEX; INNERVATING OTOLITH ORGANS; SPATIAL PROPERTIES; SQUIRREL-MONKEY; STATIC TILTS; GAIN CHANGES; GRAVITY; NUCLEUS; DEPENDENCE; RESPONSES;
D O I
10.1111/j.1749-6632.2011.06176.x
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Sixteen neurons, including vestibular-only (VO), eye-head velocity (EHV), and position-vestibular-pause (PVP) neurons sensitive to head tilt were recorded in the rostromedial and in superior vestibular nuclei. Projection of the otolith polarization vector to the horizontal plane (response vector orientation [RVO]) was determined before and after prolonged head orientation in side-down position. The RVO of VO neurons shifted toward alignment with the axis of gravity when the head was in the position of adaptation. PVP neurons had similar changes in RVO. There were also changes in RVO in some EHV neurons, but generally in directions not related to gravity. Modeling studies have suggested that the tendency to align RVOs with gravity leads to tuning of gravity-dependent angular vestibular ocular reflex (aVOR) gain changes to the position of adaptation. Thus, coding of orientation in PVP neurons would contribute significantly to the gravity-dependent adaptation of the aVOR.
引用
收藏
页码:214 / 218
页数:5
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