Asthma and suicide: Possible role of brain-derived neurotrophic factor

被引：7
|
作者：
Ozek, Esra [1 ]
Ekici, Baris [2 ]
机构：
[1] Istanbul Univ, Cerrahpasa Med Fac, Dept Pediat Allergy & Immunol, Fatih Istanbul, Turkey
[2] Istanbul Univ, Istanbul Fac Med, Dept Pediat Neurol, Fatih Istanbul, Turkey
来源：
MEDICAL HYPOTHESES | 2011年 / 77卷 / 02期
关键词：
D O I：
10.1016/j.mehy.2011.04.028
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The suicide rates among asthmatic patients are higher than among the general population. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family and is strongly associated with suicide pathogenesis. BDNF also plays an important role in neuroimmune reactions in allergic diseases such as asthma. Therefore, we hypothesize that alterations of BDNF levels in the brain may explain the increased suicide rates among asthmatic patients. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：261 / 262
页数：2
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