Advances in molecular biomarkers and liquid biopsy in gliomas

被引：2
|
作者：
Mathios, Dimitrios [1 ,2 ]
Phallen, Jillian [2 ]
机构：
[1] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Sch Med, Dept Neurosurg, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Dept Oncol, Sidney Kimmel Comprehens Canc, Baltimore, MD 21205 USA
来源：
NEURO-ONCOLOGY ADVANCES | 2022年 / 4卷
关键词：
circulating biomarker; circulating tumor DNA; glioblastoma; liquid biopsy; GLIOBLASTOMA; TEMOZOLOMIDE; MUTATIONS; RAS; DNA;
D O I：
10.1093/noajnl/vdac151
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
There have been significant strides toward understanding the molecular landscape of brain cancer. These advances have been focused on analyses of the tumor microenvironment and have recently expanded to include liquid biopsies to identify molecular biomarkers noninvasively. Moving from tissue to liquid-based analyses of molecular biomarkers has been challenging and currently, there are no approved noninvasive tests that are clinically useful. However, the emerging field of molecular liquid biopsy assay development in the neuro-oncology space has great potential to revolutionize the detection and monitoring of patients with brain cancer.
引用
收藏
页码：15 / 21
页数：7
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