Increased expression of endothelin-1 and its receptors in varicocele: an immunohistochemical study

被引：3
|
作者：
Gyftopoulos, Kostis [1 ,2 ]
Chondrogianni, Christina [1 ]
Papadaki, Helen [1 ]
机构：
[1] Univ Patras, Sch Med, Dept Anat, Rion 26500, Greece
[2] Olympion Hosp, Urol Clin, Patras, Greece
来源：
FERTILITY AND STERILITY | 2011年 / 95卷 / 08期
关键词：
Endothelin; receptors; immunohistochemistry; varicocele; SMOOTH-MUSCLE-CELLS; ADOLESCENT VARICOCELE; SPERMATIC VEINS; SHEAR-STRESS; ET-1; PATHOPHYSIOLOGY; ETIOLOGY; DISEASE;
D O I：
10.1016/j.fertnstert.2011.04.062
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
We hypothesized that diminished endothelin 1 (ET-1) expression at the spermatic vein wall level might be responsible for the development of varicocele. However, immunohistochemical evaluation of spermatic and control vein samples from 55 patients with varicocele showed overexpression of ET-1 and its receptors ETA and ETB in varicose veins. (Fertil Steril (R) 2011; 95: 2554-6. (C) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码：2554 / U583
页数：5
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