Managing thrombosis in cancer patients

被引：35

作者：

Wang, Tzu-Fei ^{[1
]}

Li, Ang ^{[2
]}

Garcia, David ^{[2
]}

机构：

[1] Ohio State Univ, Div Hematol, Columbus, OH 43210 USA

[2] Univ Washington, Sch Med, Div Hematol, Seattle, WA 98195 USA

来源：

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS | 2018年 / 2卷 / 03期

基金：

美国国家卫生研究院;

关键词：

anticoagulation; cancer-associated thrombosis; deep vein thrombosis; malignancy; pulmonary embolism; Venous thromboembolism; RECURRENT VENOUS THROMBOEMBOLISM; MOLECULAR-WEIGHT HEPARIN; DEEP-VEIN THROMBOSIS; ACTIVE CANCER; P-SELECTIN; INTRACRANIAL HEMORRHAGE; SECONDARY PREVENTION; PULMONARY-EMBOLISM; DOSE-ESCALATION; TISSUE FACTOR;

D O I：

10.1002/rth2.12102

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Venous thromboembolism is a major complication in cancer patients. The basis for the strong association between cancer and thrombosis remains incompletely understood, and the optimal approaches to both the treatment and the prevention of cancer-associated thrombosis are evolving. Here we review several important topics related to cancer-associated thromboembolism, including the pathogenesis, prevention, and management of this disease. Wherever possible, we include evidence from clinical trials, including the results of recently published trials that compared direct oral anticoagulants to low-molecular-weight heparin for the treatment of cancer-associated thrombosis.

引用

页码：429 / 438

页数：10

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