Demography and pedigree structure of an SPF colony of rhesus monkeys (Macaca mulatta)

被引:2
|
作者
Ludvico, L
Slifer, S
Massey, K
Mosman, K
Mohamed, C
Stone, W
Keeling, M
Bernacky, B
Dyke, B
机构
[1] SW Fdn Biomed Res, Dept Genet, San Antonio, TX 78284 USA
[2] Trinity Univ, Dept Biol, San Antonio, TX 78212 USA
[3] Univ Texas, MD Anderson Canc Ctr, Dept Lab Anim Med, Bastrop, TX USA
[4] SW Reg Primate Res Ctr, San Antonio, TX USA
关键词
specific pathogen free; Macaca mulatta; SPF colony management; demography; pedigree structure;
D O I
10.1002/ajp.2
中图分类号
Q95 [动物学];
学科分类号
071002 ;
摘要
The SPF rhesus colony at the M.D. Anderson Cancer Center in Bastrop, Texas, was analyzed with the aim of determining the demographic and genetic effects of stringent selection for virus-free breeders, permanent quarantine, continued surveillance, and culling of animals that show evidence of viral infection. The analysis shows minimal effects on population viability and loss of genetic variability in comparison with the traditionally managed (non-SPF) portion of the population. Am. J. Primatol. 53:155-165, 2001. (C) 2001 Wiley-Liss, Inc.
引用
收藏
页码:155 / 165
页数:11
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