Artificial Intelligence, Healthcare, Clinical Genomics, and Pharmacogenomics Approaches in Precision Medicine

被引:23
|
作者
Abdelhalim, Habiba [1 ]
Berber, Asude [1 ]
Lodi, Mudassir [1 ]
Jain, Rihi [1 ]
Nair, Achuth [1 ]
Pappu, Anirudh [1 ]
Patel, Kush [1 ]
Venkat, Vignesh [1 ]
Venkatesan, Cynthia [1 ]
Wable, Raghu [1 ]
Dinatale, Matthew [1 ]
Fu, Allyson [1 ]
Iyer, Vikram [1 ]
Kalove, Ishan [1 ]
Kleyman, Marc [1 ]
Koutsoutis, Joseph [1 ]
Menna, David [1 ]
Paliwal, Mayank [1 ]
Patel, Nishi [1 ]
Patel, Thirth [1 ]
Rafique, Zara [1 ]
Samadi, Rothela [1 ]
Varadhan, Roshan [1 ]
Bolla, Shreyas [1 ]
Vadapalli, Sreya [1 ]
Ahmed, Zeeshan [1 ,2 ]
机构
[1] Rutgers State Univ, Rutgers Inst Hlth, Hlth Care Policy & Aging Res, New Brunswick, NJ 08901 USA
[2] Rutgers Robert Wood Johnson Med Sch, Dept Med, Rutgers Biomed & Hlth Sci, New Brunswick, NJ 08901 USA
关键词
artificial intelligence; healthcare; clinical-genomics; pharmacogenomics; precision medicine; PERSONALIZED MEDICINE; DYSTROPHIN GENE; DRUG DISCOVERY; NONCODING RNAS; SEQUENCE; DATABASE; TRANSCRIPTION; CHALLENGES; MUTATIONS; BENEFITS;
D O I
10.3389/fgene.2022.929736
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Precision medicine has greatly aided in improving health outcomes using earlier diagnosis and better prognosis for chronic diseases. It makes use of clinical data associated with the patient as well as their multi-omics/genomic data to reach a conclusion regarding how a physician should proceed with a specific treatment. Compared to the symptom-driven approach in medicine, precision medicine considers the critical fact that all patients do not react to the same treatment or medication in the same way. When considering the intersection of traditionally distinct arenas of medicine, that is, artificial intelligence, healthcare, clinical genomics, and pharmacogenomics-what ties them together is their impact on the development of precision medicine as a field and how they each contribute to patient-specific, rather than symptom-specific patient outcomes. This study discusses the impact and integration of these different fields in the scope of precision medicine and how they can be used in preventing and predicting acute or chronic diseases. Additionally, this study also discusses the advantages as well as the current challenges associated with artificial intelligence, healthcare, clinical genomics, and pharmacogenomics.
引用
收藏
页数:12
相关论文
共 50 条
  • [1] Artificial intelligence, physiological genomics, and precision medicine
    Williams, Anna Marie
    Liu, Yong
    Regner, Kevin R.
    Jotterand, Fabrice
    Liu, Pengyuan
    Liang, Mingyu
    [J]. PHYSIOLOGICAL GENOMICS, 2018, 50 (04) : 237 - 243
  • [2] Exploring alternative approaches to precision medicine through genomics and artificial intelligence - a systematic review
    Mumtaz, Hassan
    Saqib, Muhammad
    Jabeen, Sidra
    Muneeb, Muhammad
    Mughal, Wajiha
    Sohail, Hassan
    Safdar, Myra
    Mehmood, Qasim
    Khan, Muhammad Ahsan
    Ismail, Syed Muhammad
    [J]. FRONTIERS IN MEDICINE, 2023, 10
  • [3] On the Role of Artificial Intelligence in Genomics to Enhance Precision Medicine
    Alvarez-Machancoses, Oscar
    DeAndres Galiana, Enrique J.
    Cernea, Ana
    Fernandez de la Vina, J.
    Fernandez-Martinez, Juan Luis
    [J]. PHARMACOGENOMICS & PERSONALIZED MEDICINE, 2020, 13 : 105 - 119
  • [4] Precision Medicine Approaches with Metabolomics and Artificial Intelligence
    Barberis, Elettra
    Khoso, Shahzaib
    Sica, Antonio
    Falasca, Marco
    Gennari, Alessandra
    Dondero, Francesco
    Afantitis, Antreas
    Manfredi, Marcello
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (19)
  • [5] Precision Psychiatry Applications with Pharmacogenomics: Artificial Intelligence and Machine Learning Approaches
    Lin, Eugene
    Lin, Chieh-Hsin
    Lane, Hsien-Yuan
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (03)
  • [6] Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare
    Yoon, Frank
    [J]. INTERNATIONAL STATISTICAL REVIEW, 2021, 89 (01) : 209 - 209
  • [7] Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare
    Wludyka, Peter
    [J]. TECHNOMETRICS, 2020, 62 (04) : 561 - 562
  • [8] Precision Medicine: Using Artificial Intelligence to Improve Diagnostics and Healthcare
    Daneshjou, Roxana
    Brenner, Steven E.
    Chen, Jonathan H.
    Crawford, Dana C.
    Finlayson, Samuel G.
    Kidzinski, Lukasz
    Bulyk, Martha L.
    [J]. BIOCOMPUTING 2022, PSB 2022, 2022, : 223 - 230
  • [9] Precision Medicine: Using Artificial Intelligence to Improve Diagnostics and Healthcare
    Whirl-Carrillo, Michelle
    Brenner, Steven E.
    Chen, Jonathan H.
    Crawford, Dana C.
    Kidzinski, Lukasz
    Ouyang, David
    Daneshjou, Roxana
    [J]. BIOCOMPUTING 2023, PSB 2023, 2023, : 257 - 262
  • [10] Application of Artificial Intelligence for Precision Medicine in Clinical Sequencing
    Furukawa, Yoichi
    [J]. PEDIATRIC BLOOD & CANCER, 2017, 64 : S4 - S5