Protein Phosphatase-1 Increases Calcium Spark Frequency in Murine Cardiomyocytes via Modulation of RyR2 Phosphorylation

被引:0
|
作者
Potenza, Duilio Michele [1 ]
Fernandez-Tenorio, Miguel [1 ]
Niggli, Ernst [1 ]
机构
[1] Univ Bern, Dept Physiol, Buhlpl 5, CH-3012 Bern, Switzerland
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
1333-Pos
引用
收藏
页码:269A / 270A
页数:7
相关论文
共 50 条
  • [1] Modulation of Ca2+ Signaling in HL-1 Cardiomyocytes by Arrhythmogenic RyR2 Mutants
    Tetsuo, Naoyuki
    Kurebayashi, Nagomi
    Murayama, Takashi
    Sakurai, Takashi
    BIOPHYSICAL JOURNAL, 2017, 112 (03) : 541A - 541A
  • [2] How phosphorylation activates the protein phosphatase-1 • inhibitor-2 complex
    Cannon, John F.
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2013, 1834 (01): : 71 - 86
  • [3] Treatment with beta-blockers normalizes RyR2 phosphorylation and calcium spark activity in atrial myocytes from patients with atrial fibrillation
    Jimenez-Sabado, V
    Casabella, S.
    Izquierdo, P.
    Tarifa, C.
    Llach, A.
    Colino, H.
    Nolla-Colomer, C.
    Ramirez, O.
    Benitez, R.
    Tauron, M.
    Rodriguez-Font, E.
    Cinca, J.
    Hove-Madsen, L.
    EUROPEAN HEART JOURNAL, 2020, 41 : 3691 - 3691
  • [4] Ablation of two Major Phosphorylation Sites in RyR2 Alter Sarcoplamic Reticulum Calcium Handling and Increases the Propensity to Atrial Fibrillation
    Mondragon, Roberto Ramos
    Camors, Emmanuel M.
    Bao, Yangyang
    Willis, Cicero B.
    Valdivia, Carmen
    Isom, Lori
    Jalife, Jose
    Valdivia, Hector H.
    BIOPHYSICAL JOURNAL, 2016, 110 (03) : 270A - 270A
  • [5] Nitroxyl (HNO) inotropy is blunted in Gaq overexpressing murine cardiomyocytes displaying increased thioredoxin-1 levels and lowered RyR2 protein expression
    Tocchetti, C. G.
    Cormaci, G.
    Aon, M. A.
    Watson, W. H.
    Kaludercic, N.
    Betocchi, S.
    Chiariello, M.
    Ii, G. W. Dorn
    Kass, D. A.
    Paolocci, N.
    EUROPEAN HEART JOURNAL, 2007, 28 : 281 - 281
  • [6] Phosphorylation of protein Phosphatase-1 isoforms by cdc2-cyclin B in vitro
    Franca Puntoni
    Emma Villa-Moruzzi
    Molecular and Cellular Biochemistry, 1997, 171 : 115 - 120
  • [7] Phosphorylation of protein phosphatase-1 isoforms by cdc2 cyclin B in vitro
    Puntoni, F
    VillaMoruzzi, E
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 1997, 171 (1-2) : 115 - 120
  • [8] Activation of endogenous protein phosphatase 1 enhances the calcium sensitivity of the ryanodine receptor type 2 in murine ventricular cardiomyocytes
    Potenza, Duilio Michele
    Janicek, Radoslav
    Fernandez-Tenorio, Miguel
    Niggli, Ernst
    JOURNAL OF PHYSIOLOGY-LONDON, 2020, 598 (06): : 1131 - 1150
  • [9] Ca2+/Calmodulin Dependent Protein Kinase II Phosphorylation of RyR2 Alters the Force-Frequency Relationship in Mice
    McCauley, Mark D.
    Wang, Tiannan
    Ather, Sameer
    Li, Na
    Bozkurt, Biykem
    Wehrens, Xander
    JOURNAL OF CARDIAC FAILURE, 2011, 17 (08) : S32 - S32
  • [10] CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1
    Zeng, Zhu
    Huang, Nina
    Zhang, Yudan
    Wang, Ying
    Su, Yufei
    Zhang, Huifang
    An, Yuan
    LIFE SCIENCES, 2020, 242