Bioactive cyclobutane-containing alkaloids

被引：285
|
作者：
Dembitsky, Valery M. [1 ]
机构：
[1] Hebrew Univ Jerusalem, Sch Pharm, Dept Med Chem & Nat Prod, IL-91120 Jerusalem, Israel
来源：
JOURNAL OF NATURAL MEDICINES | 2008年 / 62卷 / 01期
关键词：
alkaloids; cyclobutane-containing; biosynthesis; anticancer; antibacterial; activities; photodimerization; terrestrial; marine;
D O I：
10.1007/s11418-007-0166-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The present review describes research on novel natural cyclobutane-containing alkaloids and synthetic compounds isolated from terrestrial and marine species. More than 210 compounds have been confirmed to show antimicrobial, antibacterial, anticancer, and other activities. Structures, origins, biosynthesis, photodimerization, and biological activities of a selection of cyclobutane-containing alkaloids and selected synthethic analogs of natural alkaloids are reviewed.
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页码：1 / 33
页数：33
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