Assessment of factors associated with the quality of life of patients living with HIV/HCV co-infection

被引：8

作者：

Pereira, Marco ^{[1
]}

Fialho, Renata ^{[2
,3
]}

机构：

[1] Univ Coimbra, Fac Psychol & Educ Sci, Rua Colegio Novo, P-3000315 Coimbra, Portugal

[2] Univ Sussex, Sch Psychol, Brighton, E Sussex, England

[3] Sussex Partnership NHS Fdn Trust, Brighton, E Sussex, England

来源：

JOURNAL OF BEHAVIORAL MEDICINE | 2016年 / 39卷 / 05期

关键词：

Co-infection; HIV; HCV; Psychological symptoms; Quality of life; CHRONIC HEPATITIS-C; HUMAN-IMMUNODEFICIENCY-VIRUS; HIV-INFECTED PATIENTS; ANTIRETROVIRAL THERAPY; MENTAL-HEALTH; DRUG-USERS; DEPRESSIVE SYMPTOMS; EMOTIONAL DISTRESS; VIRAL-HEPATITIS; SUBSTANCE USE;

D O I：

10.1007/s10865-016-9778-y

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

This study compared the quality of life (QoL) of HIV-infected patients with and without hepatitis C and examined the sociodemographic, HIV-related and psychological symptoms associated with the QoL domains in patients with HIV/HCV co-infection. The sample consisted of 248 HIV/HCV co-infected patients (18-74 years, 81.5 % male) and 482 patients only with HIV (24-78 years, 62.7 % male). Participants completed the WHOQOL-HIV-Bref questionnaire and the Brief Symptom Inventory. The HIV/HCV co-infected patients reported significantly lower QoL in all domains, as well as significantly lower scores in 10 of the 17 specific facets. Overall, among the co-infected patients, male gender, employment, combination antiretroviral therapy use and fewer depressive and anxiety symptoms were significantly associated with higher QoL. Symptoms of psychological distress accounted for significant variability in the QoL scores of co-infected patients. These data reinforce the need for tailored interventions to improve the overall well-being of HIV/HCV co-infected patients.

引用

页码：767 / 781

页数：15

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