Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes

被引：59
|
作者：
Kiokias, Sotirios [1 ]
Proestos, Charalampos [2 ]
Oreopoulou, Vassilki [3 ]
机构：
[1] REA, B-1049 Brussels, Belgium
[2] Natl & Kapodistrian Univ Athens, Lab Food Chem, Dept Chem, Athens 15784, Greece
[3] Natl Tech Univ Athens, Lab Food Chem & Technol, Sch Chem Engn, Iron Politech 9, Athens 15780, Greece
来源：
ANTIOXIDANTS | 2018年 / 7卷 / 10期
关键词：
LDL-oxidation; DNA-damage; antioxidant vitamins; oxidative stress; LOW-DENSITY-LIPOPROTEIN; CAROTENOIDS IN-VITRO; VITAMIN-C; ALPHA-TOCOPHEROL; LIPID-PEROXIDATION; PHENOLIC-COMPOUNDS; COMET ASSAY; STRAND BREAKS; DAMAGE; STRESS;
D O I：
10.3390/antiox7100133
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids; vitamins C and E) to monitor LDL and DNA oxidative changes.
引用
收藏
页数：20
相关论文
共 50 条
  • [1] EFFECT OF ANTIOXIDANTS ON OXIDATIVE MODIFICATION OF LDL
    ESTERBAUER, H
    PUHL, H
    DIEBERROTHENEDER, M
    WAEG, G
    RABL, H
    ANNALS OF MEDICINE, 1991, 23 (05) : 573 - 581
  • [2] THE EFFECT OF NATURAL ANTIOXIDANTS ON THE OXIDATIVE PROCESSES IN BEEF
    Karwowska, Malgorzata
    Dolatowski, Zbigniew J.
    ACTA SCIENTIARUM POLONORUM-TECHNOLOGIA ALIMENTARIA, 2007, 6 (01) : 17 - 25
  • [3] Antiatherogenicity of antioxidants against LDL oxidation
    Aviram, M
    NATURAL ANTIOXIDANTS AND ANTICARCINOGENS IN NUTRITION, HEALTH AND DISEASE, 1999, (240): : 9 - 19
  • [4] The effect of natural and synthetic antioxidants on the oxidative stability of biodiesel
    Tang, Haiying
    Wang, Anfeng
    Salley, Steven O.
    Ng, K. Y. Simon
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2008, 85 (04) : 373 - 382
  • [5] ANTIOXIDANTS AND RESISTANCE AGAINST OXIDATION OF PIG LDL
    KNIPPING, G
    ROTHENEDER, M
    STRIEGL, G
    ESTERBAUER, H
    ARTERIOSCLEROSIS, 1990, 10 (05): : A796 - A797
  • [6] The effect of natural and synthetic antioxidants on the oxidative stability of palm diesel
    Liang, YC
    May, CY
    Foon, CS
    Ngan, MA
    Chuah, CH
    Basiron, Y
    FUEL, 2006, 85 (5-6) : 867 - 870
  • [7] IN SEARCH OF BETTER METHODS TO EVALUATE NATURAL ANTIOXIDANTS AND OXIDATIVE STABILITY IN FOOD LIPIDS
    FRANKEL, EN
    TRENDS IN FOOD SCIENCE & TECHNOLOGY, 1993, 4 (07) : 220 - 225
  • [8] Protection Effect of a Combination of Antioxidants on Oxidative DNA Damage of Mice
    Ke, Y.
    JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE, 2011, 50 (05): : 800 - 801
  • [9] ANTIOXIDANTS AND RESISTANCE AGAINST OXIDATION OF PORCINE LDL SUBFRACTIONS
    KNIPPING, G
    ROTHENEDER, M
    STRIEGL, G
    ESTERBAUER, H
    JOURNAL OF LIPID RESEARCH, 1990, 31 (11) : 1965 - 1972
  • [10] Oxidative Stress and Alleviating Effect of Natural Antioxidants on Alzheimer's Disease*
    Zhao, Bao-Lu
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 50 (05) : 1144 - 1158
12345