Mycosis fungoides;
Cutaneous T-cell lymphoma;
Ultraviolet;
Phototherapy;
Narrowband UVB;
Psoralen and ultraviolet A;
Psoralen;
BAND ULTRAVIOLET-B;
ORAL METHOXSALEN PHOTOCHEMOTHERAPY;
EARLY MYCOSIS-FUNGOIDES;
TERM-FOLLOW-UP;
SKIN-CANCER;
SEZARY-SYNDROME;
INTERNATIONAL-SOCIETY;
EUROPEAN-ORGANIZATION;
CONSENSUS STATEMENT;
COMPLETE REMISSION;
D O I:
10.1016/j.det.2019.08.013
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
Phototherapy with psoralen and ultraviolet A (PUVA) or narrowband-UVB (NBUVB) is frequently used for the patch and plaque stages of mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma. This article provides practical guidelines for the design and implementation of a phototherapy protocol for early stage MF, including an overview of treatment phases, response criteria, and considerations in the selection of a light source. Several evolving topics in phototherapy research are also discussed, including the relative efficacy of PUVA versus NBUVB, the role of maintenance therapy, risk of photocarcinogenicity, and combination therapies.
机构:
Karl Landsteiner Univ Hlth Sci, Univ Hosp St Polten, Dept Dermatol & Venereol, Krems An Der Donau, Austria
Karl Landsteiner Inst Dermatol Res, St Polten, AustriaKarl Landsteiner Univ Hlth Sci, Univ Hosp St Polten, Dept Dermatol & Venereol, Krems An Der Donau, Austria