Diagnosis of Helicobacter pylori infection

被引:13
|
作者
Bessede, Emilie [1 ,2 ]
Arantes, Vitor [3 ,4 ]
Megraud, Francis [1 ,2 ]
Coelho, Luiz Gonzaga [3 ,4 ]
机构
[1] Univ Bordeaux, INSERM U1053, Bordeaux, France
[2] CHU Bordeaux, Natl Reference Ctr Helicobacters, Bacteriol Lab, Bordeaux, France
[3] Univ Fed Minas Gerais, Alfa Inst Gastroenterol, Clin Hosp, Belo Horizonte, MG, Brazil
[4] Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
关键词
biomarker; magnifying endoscopy; PCR; SAT; serology; UBT; BREATH TEST; CLARITHROMYCIN RESISTANCE; GASTRIC-CANCER; UREASE TEST; STOOL; ACCURACY; PCR; C-13-UREA; IMMUNOASSAY; ERADICATION;
D O I
10.1111/hel.12404
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Important progress is being made in endoscopic methods which allow clinicians to predict the presence of Helicobacter pylori based on characteristics of gastric mucosa and to obtain targeted biopsies. There are also important developments in molecular methods with various techniques derived from standard PCR, applied both on gastric biopsies and stool specimens. Progress is being made in microfluidic systems to get a reliable diagnosis in a very short time. The interest of the C-13 urea breath test has been confirmed as well as stool antigen tests. Attempts are being made to find biological markers of premalignant conditions by serology, other than pepsinogens.
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页数:6
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