Sodium-Glucose Cotransporter-2 Inhibitors: Heart Failure and Renal Protection Indications

被引:2
|
作者
El Hussein, Mohamed Toufic [1 ,2 ,3 ]
Bell, Nicole [4 ]
机构
[1] Mt Royal Univ Calgary, Fac Hlth Community & Educ, Sch Nursing & Midwifery, Calgary, AB, Canada
[2] Univ Calgary Calgary, Fac Nursing, Calgary, AB, Canada
[3] Rockyview Gen Hosp Calgary, Coronary Care Unit, Med Cardiol, Calgary, AB, Canada
[4] Mt Royal Univ, Calgary, AB, Canada
来源
关键词
heart failure; renal failure; sodium-glucose cotransporter-2 inhibitors; type; 2; diabetes; CARDIOVASCULAR EVENTS; EMPAGLIFLOZIN; RATIONALE; DESIGN; RISK;
D O I
10.1016/j.nurpra.2021.09.002
中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) are a class of oral antihyperglycemic drugs recently added to clinical practice guidelines to manage type 2 diabetes mellitus (T2DM). Recent clinical trials have established significant benefits in using SGLT-2is to treat both heart failure and renal disease. This article aims to explain the clinical benefits of inhibiting sodium-glucose cotransporter-2 proteins in patients with T2DM, renal disease, and heart failure. These authors also seek to guide nurse practitioners in prescribing SGLT-2is. Evidence-based guidance for nurse practitioners to treat T2DM, heart failure, and renal disease is likely to improve patients' clinical outcomes and decrease associated morbidities. (c) 2021 Elsevier Inc. All rights reserved.
引用
收藏
页码:179 / 184
页数:6
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