A Strategy for Depositing Different Types of Cells in Three Dimensions to Mimic Tubular Structures in Tissues

被引:227
|
作者
Yuan, Bo [1 ]
Jin, Yu [1 ]
Sun, Yi [1 ]
Wang, Dong [1 ]
Sun, Jiashu [1 ]
Wang, Zhuo [1 ]
Zhang, Wei [1 ]
Jiang, Xingyu [1 ]
机构
[1] Natl Ctr NanoSci & Technol China, Beijing 100190, Peoples R China
基金
中国国家自然科学基金;
关键词
tubes; 3D cell patterns; artificial vessels; electrospun fibers; rolling membrane; PATTERNING MULTIPLE TYPES; BLOOD-VESSEL; MICROFLUIDIC CHANNELS; POLY(DIMETHYLSILOXANE); NANOTECHNOLOGY; CONSTRUCTS; TUBES;
D O I
10.1002/adma.201104589
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The fabrication of tubular structures, with multiple cell types forming different layers of the tube walls, is described using a stress-induced rolling membrane (SIRM). Cell orientation inside the tubes can also be controlled by topographical contact guidance. These layered tubes precisely mimic blood vessels and many other tubular structures, suggesting that they may be of great use in tissue engineering.
引用
收藏
页码:890 / +
页数:8
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