Evaluation of an estimation of physiologic ability and surgical stress (E-PASS) scoring system to predict postoperative risk: A multicenter prospective study

We previously reported generating a scoring system termed E-PASS that predicted postsurgical risk. This study was undertaken to evaluate the usefulness of this system. A consecutive series of 902 patients who underwent elective gastrointestinal operations in six national hospitals in Japan were prospectively assessed for a comprehensive risk score (CRS) of the E-PASS, which was compared with their postoperative course. The postoperative morbidity rates linearly in creased as the CRS increased. The postoperative mortality rate was only 0.13%, when the CRS was below 0.5; however, it increased to 9.7% when the CRS ranged from 0.5 to <1.0, and to 26.9% when the CRS was greater than or equal to1.0. The CRS correlated significantly with the severity of postoperative complications (r(s) = 0.527, P < 0.0001) and the costs of hospital stay (r(3) = 0.810, P < 0.0001). When the CRS-adjusted mortality rate at the CRS of greater than or equal to0.5 was compared among the hospitals, it was related to the hospital volume of operations, being 44.2% at the volume of < 100 cases per year, 20.6% at the range of 100-199 cases, and 8.6% at the volume of greater than or equal to 200 cases. These results suggest that E-PASS may be useful for predicting postsurgical risk, estimating medical expense, and comparing surgical quality.