Seroprevalence of bovine viral diarrhea virus antibodies and risk factors in dairy cattle from the central desert of Iran

Bovine viral diarrhea virus (BVDV) infects cattle worldwide and causes one of the most important economic diseases of the dairy industry. BVDV infection reduces reproductive efficiency, suppresses the immune system, and causes gastrointestinal and respiratory diseases. A first cross-sectional study was conducted in the central desert of Iran (Yazd and South Khorasan provinces) to estimate the seroprevalence and identify BVDV-related risk factors in dairy cattle. A total of 800 cows were randomly selected of 76 herds, and their serum samples were tested by the indirect enzyme-linked immunosorbent assay (ELISA) method for BVDV antibody detection. Data were analyzed using the logistic regression model. The serum prevalence of BVDV at animal and herd levels was 66.83% and 91.6%, respectively. Traditional housing system (OR= 3.22; 95% CI =1.20-9.09) and cattle introduction to the herd (OR =2.12; 95% CI = 1.21-3.70) were the important risk factors for BVDV seropositivity (p < 0.05). Increasing of age per year caused adding in 0.33 log (odds) of BVDV seropositivity (p < 0.05). It is necessary to implement control and eradication programs because of the high seroprevalence at the individual level and at the herd in the central desert of Iran.