Multigene Panel Testing for Hereditary Cancer and Genetic Counseling

被引：3
|
作者：
Lee, Eun-Shin [1 ]
Kim, Jongjin [2 ]
Han, Wonshik [1 ]
机构：
[1] Seoul Natl Univ Hosp, Seoul, South Korea
[2] SMG SNU Boramae Med Ctr, Seoul, South Korea
来源：
TRANSLATIONAL RESEARCH IN BREAST CANCER | 2021年 / 1187卷
关键词：
Hereditary/familial breast cancer; Breast cancer susceptibility; Multigene panel testing; Next-generation sequencing; High penetrance gene; Genetic counseling; BRCA1/2 gene mutation; BREAST; RISK; OVARIAN; MUTATIONS;
D O I：
10.1007/978-981-32-9620-6_24
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
As sequencing technology and information of the genomic causes for cancer development expand, multi-gene panel testing for hereditary cancer is increasing in clinical practice. In this chapter, we reviewed the application of multi-gene panel with pre-/post- testing considerations and summarized genetic counseling based on panel testing results in clinical field. In addition, we introduce multi-gene panel for hereditary cancer developed in Seoul National University Hospital.
引用
收藏
页码：455 / 471
页数：17
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