Dietary Melanoidins from Biscuits and Bread Crust Alter the Structure and Short-Chain Fatty Acid Production of Human Gut Microbiota

被引:12
|
作者
Rajakaruna, Sumudu [1 ]
Perez-Burillo, Sergio [1 ,2 ]
Kramer, Denise Lynette [1 ]
Rufian-Henares, Jose Angel [2 ]
Paliy, Oleg [1 ]
机构
[1] Wright State Univ, Boonshoft Sch Med, Dept Biochem & Mol Biol, Dayton, OH 45435 USA
[2] Univ Granada, Ctr Invest Biomed CIBM, Inst Nutr & Tecnol Alimentos, Dept Nutr & Bromatol, E-18071 Granada, Spain
关键词
melanoidins; gut microbiota; short-chain fatty acids; antioxidant capacity; human microbiome;
D O I
10.3390/microorganisms10071268
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Melanoidins are the products of the Maillard reaction between carbonyl and amino groups of macromolecules and are readily formed in foods, especially during heat treatment. In this study we utilized the three-stage Human Gut Simulator system to assess the effect of providing melanoidins extracted from either biscuits or bread crust to the human gut microbiota. Addition of melanoidins to the growth medium led to statistically significant alterations in the microbial community composition, and it increased short-chain fatty acid and antioxidant production by the microbiota. The magnitude of these changes was much higher for cultures grown with biscuit melanoidins. Several lines of evidence indicate that such differences between these melanoidin sources might be due to the presence of lipid components in biscuit melanoidin structures. Because melanoidins are largely not degraded by human gastrointestinal enzymes, they provide an additional source of microbiota-accessible nutrients to our gut microbes.
引用
收藏
页数:14
相关论文
共 50 条
  • [1] Genomic reconstruction of short-chain fatty acid production by the human gut microbiota
    Frolova, Maria S.
    Suvorova, Inna A.
    Iablokov, Stanislav N.
    Petrov, Sergei N.
    Rodionov, Dmitry A.
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 9
  • [2] Guided dietary fibre intake as a means of directing short-chain fatty acid production by the gut microbiota
    Tannock, Gerald W.
    Liu, Yafei
    JOURNAL OF THE ROYAL SOCIETY OF NEW ZEALAND, 2020, 50 (03) : 434 - 455
  • [3] In vitro Short-Chain Fatty Acid Production of Rice Bran Components by Human Gut Microbiota
    Pham, Tung
    Savary, Brett J.
    Chen, Ming-Hsuan
    Lee, Sun-Ok
    FASEB JOURNAL, 2016, 30
  • [4] Associations of gut microbiota, dietary intake, and serum short-chain fatty acids with fecal short-chain fatty acids
    Yamamura, Ryodai
    Nakamura, Koshi
    Kitada, Naoya
    Aizawa, Tomoyasu
    Shimizu, Yu
    Nakamura, Kiminori
    Ayabe, Tokiyoshi
    Kimura, Takashi
    Tamakoshi, Akiko
    BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH, 2020, 39 (01) : 11 - 17
  • [5] Therapeutic potential of short-chain fatty acid production by gut microbiota in neurodegenerative disorders
    Yadav, Sarika
    Dwivedi, Ashish
    Tripathi, Anurag
    Tripathi, Amit Kumar
    NUTRITION RESEARCH, 2022, 106 : 72 - 84
  • [6] Effect of resistant starch structure on short-chain fatty acids production by human gut microbiota fermentation in vitro
    Zhou, Zhongkai
    Cao, Xiaohong
    Zhou, Julia Y. H.
    STARCH-STARKE, 2013, 65 (5-6): : 509 - 516
  • [7] Short-Chain Fatty Acid Production by Gut Microbiota Predicts Treatment Response in Multiple Myeloma
    Rodriguez-Garcia, Alba
    Arroyo, Andres
    Garcia-Vicente, Roberto
    Morales, Maria Luz
    Gomez-Gordo, Ruben
    Justo, Pablo
    Cuellar, Clara
    Sanchez-Pina, Jose
    Lopez, Nieves
    Alonso, Rafael
    Puig, Noemi
    Mateos, Maria-Victoria
    Ayala, Rosa
    Gomez-Garre, Dulcenombre
    Martinez-Lopez, Joaquin
    Linares, Maria
    CLINICAL CANCER RESEARCH, 2024, 30 (04) : 904 - 917
  • [8] Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior
    Evelyn Medawar
    Sven-Bastiaan Haange
    Ulrike Rolle-Kampczyk
    Beatrice Engelmann
    Arne Dietrich
    Ronja Thieleking
    Charlotte Wiegank
    Charlotte Fries
    Annette Horstmann
    Arno Villringer
    Martin von Bergen
    Wiebke Fenske
    A. Veronica Witte
    Translational Psychiatry, 11
  • [9] Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior
    Medawar, Evelyn
    Haange, Sven-Bastiaan
    Rolle-Kampczyk, Ulrike
    Engelmann, Beatrice
    Dietrich, Arne
    Thieleking, Ronja
    Wiegank, Charlotte
    Fries, Charlotte
    Horstmann, Annette
    Villringer, Arno
    von Bergen, Martin
    Fenske, Wiebke
    Veronica Witte, A.
    TRANSLATIONAL PSYCHIATRY, 2021, 11 (01)
  • [10] Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota
    Fusco, William
    Lorenzo, Manuel Bernabeu
    Cintoni, Marco
    Porcari, Serena
    Rinninella, Emanuele
    Kaitsas, Francesco
    Lener, Elena
    Mele, Maria Cristina
    Gasbarrini, Antonio
    Collado, Maria Carmen
    Cammarota, Giovanni
    Ianiro, Gianluca
    NUTRIENTS, 2023, 15 (09)