p85α subunit of class IA PI-3Kinase plays an essential role in regulating growth and actin based functions in macrophages.

被引:0
|
作者
Munugalavadla, V [1 ]
Ingram, DA [1 ]
Kapur, R [1 ]
机构
[1] Indiana Univ, Sch Med, Herman B Wells Ctr Pediat Res, Dept Pediat, Indianapolis, IN USA
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
3880
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页码:44B / 44B
页数:1
相关论文
共 27 条
  • [1] p85α regulatory subunit of class IA PI-3Kinase regulates osteoclast function(s) and bone mass.
    Munugalavadla, V
    Sims, E
    Ingram, DA
    Robling, A
    Kapur, R
    [J]. BLOOD, 2005, 106 (11) : 627A - 627A
  • [2] p85α subunit of class IA PI-3 kinase is crucial for macrophage growth and migration
    Munugalavadla, V
    Borneo, J
    Ingram, DA
    Kapur, R
    [J]. BLOOD, 2005, 106 (01) : 103 - 109
  • [3] Differential role for p5α and p85β regulatory subunits of class IA PI-3Kinase in mast cell growth and maturation.
    Munugalavadla, V
    Hong, L
    White, H
    Ingram, DA
    Kapur, R
    [J]. BLOOD, 2004, 104 (11) : 594A - 595A
  • [4] p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis
    Krishnan, Subha
    Mali, Raghuveer Singh
    Ramdas, Baskar
    Sims, Emily
    Ma, Peilin
    Ghosh, Joydeep
    Munugalavadla, Veerendra
    Hanneman, Philip
    Beane, Joal D.
    Kapur, Reuben
    [J]. BLOOD, 2012, 119 (17) : 3951 - 3961
  • [5] Class IA PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes
    Krishnan, Subha
    Mali, Raghuveer Singh
    Koehler, Karl R.
    Vemula, Sasidhar
    Chatterjee, Anindya
    Ghosh, Joydeep
    Ramdas, Baskar
    Ma, Peilin
    Hashino, Eri
    Kapur, Reuben
    [J]. PLOS ONE, 2012, 7 (01):
  • [6] Role of PI3 kinase p85α subunit on the development of acute colitis in mice
    Hayashi, Shusaku
    [J]. JOURNAL OF PHARMACOLOGICAL SCIENCES, 2015, 128 (03) : S98 - S98
  • [7] Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class IA Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation
    Ma, Peilin
    Vemula, Sasidhar
    Munugalavadla, Veerendra
    Chen, Jinbiao
    Sims, Emily
    Borneo, Jovencio
    Kondo, Takako
    Ramdas, Baskar
    Mali, Raghuveer Singh
    Li, Shuo
    Hashino, Eri
    Takemoto, Clifford
    Kapur, Reuben
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2011, 31 (19) : 4052 - 4062
  • [8] The p85α regulatory subunit of class IA phosphoinositide 3-kinase regulates β-selection in thymocyte development
    Shiroki, Fumiko
    Matsuda, Satoshi
    Doi, Tomomitsu
    Fujiwara, Mari
    Mochizuki, Yoshito
    Kadowaki, Takashi
    Suzuki, Harumi
    Koyasu, Shigeo
    [J]. JOURNAL OF IMMUNOLOGY, 2007, 178 (03): : 1349 - 1356
  • [9] Genetic and pharmacologic evidence implicating the p85α, but not p85β, regulatory subunit of PI-3Kinase and Rac2 GTPase in regulating oncogenic kit induced transformation in acute myeloid leukemia and systemic mastocytosis.
    Munugalavadla, V.
    Sims, E. C.
    Kapur, R.
    [J]. PEDIATRIC RESEARCH, 2007, 62 (04) : 519 - 519
  • [10] Opposing roles for class IA PI-3Kinase and Src family kinase in regulating myeloid cell growth and lineage commitment.
    Munugalavadla, V
    Borneo, J
    Chen, JB
    Kapur, R
    [J]. BLOOD, 2004, 104 (11) : 964A - 964A