Methodological Considerations in N-of-1 Trials of Traditional Chinese Medicine

被引：2
|
作者：
Huang, Haiyin [1 ]
An, Jiaqi [1 ]
Lu, Lizhi [1 ]
Wang, Mingli [1 ]
Chen, Huijia [1 ]
Chen, Xinlin [2 ]
Shen, Lihua [1 ]
机构：
[1] Shanghai Univ Tradit Chinese Med, Yueyang Hosp Integrated Tradit Chinese & Western, Shanghai 200437, Peoples R China
[2] Guangzhou Univ Tradit Chinese Med, Basic Med Coll, Guangzhou 510006, Guangdong, Peoples R China
来源：
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2021年 / 2021卷
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1155/2021/6634134
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
More and more scholars choose N-of-1 trials for TCM clinical research. However, the quality of the experimental designs was uneven. Accumulating more than eight years of experience in exploring the N-of-1 trials of TCM, the authors and their team searched the related literature in main Chinese and English databases, referenced to relevant Chinese and international guidelines. The design, implementation, and data analysis of N-of-1 trials of TCM are still in in-depth exploration and practice. "Carryover effect" may affect the design and quality of the trials. Individualized treatment should be guided by the classic theories of TCM. It is expected to formulate reasonable observation periods and pairs and closely integrate individual and group statistical analysis.
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页数：11
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