Dietary models of insulin resistance

被引：37

作者：

Deer, James ^{[1
]}

Koska, Juraj ^{[1
]}

Ozias, Marlies ^{[1
]}

Reaven, Peter ^{[1
]}

机构：

[1] Phoenix VA Hlth Care Syst, Dept Endocrinol, Phoenix, AZ 85012 USA

来源：

METABOLISM-CLINICAL AND EXPERIMENTAL | 2015年 / 64卷 / 02期

关键词：

Insulin resistance; Dietary composition; Carbohydrate; Fat; MONOUNSATURATED FATTY-ACIDS; GLUCOSE-METABOLISM; CARDIOVASCULAR-DISEASE; HUMAN MONOCYTES; SENSITIVITY; FRUCTOSE; WOMEN; OVERWEIGHT; EXPRESSION; SECRETION;

D O I：

10.1016/j.metabol.2014.08.013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Insulin resistance is a significant factor in the development of type 2 diabetes mellitus, however the connection between the Western diet and the development of insulin resistance has not been fully explained. Dietary macronutrient composition has been examined in a number of articles, and diets enriched in saturated fatty acids, and possibly in fructose, appear to be most consistently associated with the development of insulin resistance. However, mechanistic insights into the metabolic effects of such diets are lacking, and merit further study. Published by Elsevier Inc.

引用

页码：163 / 171

页数：9

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