Development of in vivo diagnosis of pathologic protein deposits in the brains of prion disease patients

被引:0
|
作者
Smid, Lojze M. [1 ,2 ]
Bresjanac, Mara [1 ]
机构
[1] MF UL, Inst Patol Fiziol, Lab Regeneracijo & Plasticnost Zivcevja, Ljubljana 1000, Slovenia
[2] Interna Klin UKC Ljubljana, Klin Oddelek Gastroenterol, Ljubljana 1000, Slovenia
来源
关键词
amyloid; FDDNP; conformational diseases; neurodegeneration; PET;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Translational medicine is a term describing systematic efforts for adequate testing and transfer of basic research findings into clinical practice. The paper outlines a series of studies aimed at evaluating a diagnostic potential of positron emission tomography with a radioisotope probe [18F]FDDNP for early recognition of pathologic protein deposits in the brains of prion disease patients. Slovene scientists contributed significantly to all studies in this bench-to-bedside sequence of translational neuroscience.
引用
收藏
页码:971 / 974
页数:4
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