Syn diastereoselectivity in the synthesis of homoallylamine using crotylsilane in the three-component reaction

被引：38
|
作者：
Billet, M [1 ]
Klotz, P [1 ]
Mann, A [1 ]
机构：
[1] Fac Pharm Illkirch, URM 7081, Lab Pharmacochim Commun Cellulaire, F-67401 Illkirch Graffenstaden, France
来源：
TETRAHEDRON LETTERS | 2001年 / 42卷 / 04期
关键词：
crotylsilane; three-component; homoallylamines; iminiums; pyrrolidines; piperidines;
D O I：
10.1016/S0040-4039(00)02025-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Crotylsilane was used in a three-component reaction for the synthesis of homoallylamines from aldehydes. A moderate to good syn/anti 5/1 diastereoselectivity was observed. The obtained homoallylamines were transformed into pyrrolidines or piperidines. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：631 / 634
页数：4
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