Mycophenolate mofetil-induced villous atrophy

被引：66
|
作者：
Ducloux, D [1 ]
Ottignon, Y
Semhoun-Ducloux, S
Labbé, S
Saint-Hillier, Y
Miguet, JP
Carayon, P
Chalopin, JM
机构：
[1] CHU St Jacques, Dept Nephrol & Renal Transplantat, F-25000 Besancon, France
[2] CHU St Jacques, Dept Gastroenterol, F-25000 Besancon, France
[3] CHU St Jacques, Dept Hepatol, F-25000 Besancon, France
来源：
TRANSPLANTATION | 1998年 / 66卷 / 08期
关键词：
D O I：
10.1097/00007890-199810270-00027
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Mycophenolate mofetil (MMF) is a new immunosuppressant developed for the prevention and treatment of acute renal rejection after transplantation. Diarrhea is the most frequent side effect observed during treatment with MMF. Its pathogenic mechanisms remain unknown. We describe a case of severe diiarrhea due to villous atrophy in a renal transplant recipient during treatment with MMF. The patient was free of symptoms before MMF. Villous atrophy disappeared a few months after MMF withdrawal.
引用
收藏
页码：1115 / 1116
页数：2
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