Unresectable Hilar Cholangiocarcinoma: Multimodality Treatment with Percutaneous and Intraluminal Plus External Radiotherapy

被引:10
|
作者
Golfieri, R. [1 ]
Giampalma, E. [1 ]
Fusco, F. [1 ]
Galuppi, A. [2 ]
Faccioli, L. [1 ]
Galaverni, C. [1 ]
Frezza, G. [3 ]
机构
[1] Azienda Osped, Policlin S Orsola Malpighi, Dipartimento Area Radiol, Unita Operat Radiol Albertoni, Bologna, Italy
[2] Azienda Osped, Policlin S Orsola Malpighi, Dipartimento Area Radiol, Unita Operat Radioterapia, Bologna, Italy
[3] Azienda USL, Unita Operat Radioterapia, Citta Di Bologna, Italy
关键词
Hepatic hilar cholangiocarcinoma; radiotherapy; brachytherapy; palliative treatment;
D O I
10.1080/1120009X.2004.11782386
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The efficacy of multimodality treatment for unresectable hilar cholangiocarcinoma was evaluated in terms of outcome, survival and quality of life. Eleven patients were enrolled in the following protocol: percutaneous drainage of both right and left biliary systems; Iridium-192 intraluminal brachytherapy; replacement of the drainages with endoprotheses; external radiotherapy. Six patients completed the protocol and 5 were treated with brachytherapy alone. Mean survival was 10.5 months, similar to surgical results and higher than the control group treated with percutaneous stenting (2.75 months) or biliary drainage alone (1.75 months), with an average hospital stay of 10-15 days and no procedure-related mortality.
引用
收藏
页码:55 / 57
页数:3
相关论文
共 50 条
  • [1] Unresectable hilar cholangiocarcinoma: Multimodality approach with percutaneous treatment associated with radiotherapy and chemotherapy
    Golfieri, R.
    Giampalma, E.
    Renzulli, M.
    Galuppi, A.
    Vicenzi, L.
    Galaverni, M. C.
    Cappelli, A.
    [J]. IN VIVO, 2006, 20 (6A): : 757 - 760
  • [2] Percutaneous biliary stenting combined with radiotherapy as a treatment for unresectable hilar cholangiocarcinoma
    Tan, Yong
    Zhu, Jian-Yong
    Qiu, Bao-An
    Xia, Nian-Xin
    Wang, Jing-Han
    [J]. ONCOLOGY LETTERS, 2015, 10 (04) : 2537 - 2542
  • [3] Length and quality of survival following external beam radiotherapy for unresectable hilar cholangiocarcinoma
    Shinchi, H
    Takao, S
    Uchikura, K
    Kubo, M
    Nishida, T
    Arima, T
    Aikou, T
    [J]. GASTROENTEROLOGY, 1999, 116 (04) : A502 - A502
  • [4] The Role of External Beam Radiotherapy with or without Concurrent Chemotherapy in the Treatment for Unresectable Locally Advanced Hilar Cholangiocarcinoma
    Huang, P.
    Chen, Y.
    Hu, Y.
    Shiau, C.
    Liu, Y.
    Wang, L.
    Chao, Y.
    Yen, S.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2011, 81 (02): : S352 - S352
  • [5] Multimodality treatment in unresectable cholangiocarcinoma
    Aphili, Mandi
    Saberi, Hazhir
    Zadeh, Mahtab Mojtahed
    Jafari, Fatemeh
    Mehrabinejad, Mohammad-Mehdi
    Dashti, Habibollah
    Saberi, Pejman
    Yazdi, Niloofar Ayoobi
    [J]. JOURNAL OF CONTEMPORARY BRACHYTHERAPY, 2020, 12 (02) : 131 - 138
  • [6] The role of multimodality therapy (MMT) in unresectable hilar cholangiocarcinoma (UHC).
    Bhadkamkar, N. A.
    Kar, S. P.
    Weatherly, J.
    Garrett, C. R.
    Vauthey, J.
    Kaseb, A. O.
    Das, P.
    Javle, M. M.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [7] UNRESECTABLE HILAR CHOLANGIOCARCINOMA - PERCUTANEOUS VERSUS OPERATIVE PALLIATION
    NORDBACK, IH
    PITT, HA
    COLEMAN, J
    VENBRUX, AC
    DOOLEY, WC
    YEU, NN
    CAMERON, JL
    [J]. SURGERY, 1994, 115 (05) : 597 - 603
  • [8] EXTERNAL RADIOTHERAPY FOR BILIARY DECOMPRESSION OF HILAR CHOLANGIOCARCINOMA
    OHNISHI, H
    ASADA, M
    SHICHIJO, Y
    IIJIMA, Y
    ITOBAYASHI, E
    SHIMURA, K
    SUZUKI, T
    YOSHIDA, S
    MINE, T
    [J]. HEPATO-GASTROENTEROLOGY, 1995, 42 (03) : 265 - 268
  • [9] Unresectable hilar cholangiocarcinoma completely reduced by external radiation therapy
    Kaido, T
    Imamura, M
    [J]. HEPATO-GASTROENTEROLOGY, 2005, 52 (63) : 725 - 727
  • [10] Impact of Intraoperative Radiotherapy (IORT) on Survival of Patients with Unresectable Hilar Cholangiocarcinoma
    Kaiser, Gernot Maximilian
    Fruehauf, Nils Roman
    Lang, Hauke
    Sauerwein, Wolfgang
    Sotiropoulos, Georglos C.
    Zoepf, Thomas
    Grabellus, Florian
    Wittig, Andrea
    Oldhafer, Karl Juergen
    Malago, Massimo
    Broelsch, Chriqtbph E.
    [J]. HEPATO-GASTROENTEROLOGY, 2008, 55 (88) : 1951 - 1954